Ethionamide

Ethionamide is an antimycobacterial compound that is active against M. tuberculosis (MICs = 0.3-1.25 µg/ml). It is activated via oxidation by flavin monooxygenase and inhibits the InhA enzyme involved in mycolic acid biosynthesis. Formulations containing ethionamide have been used in the second-line treatment of multi-drug resistant tuberculosis.Formal Name: 2-ethyl-4-pyridinecarbothioamide. CAS Number: 536-33-4. Synonyms: NSC 255115. Molecular Formula: C8H10N2S. Formula Weight: 166.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble, Methanol: Slightly Soluble. lambdamax: 290 nm. SMILES: CCC1=CC(C(N)=S)=CC=N1. InChi Code: InChI=1S/C8H10N2S/c1-2-7-5-6(8(9)11)3-4-10-7/h3-5H,2H2,1H3,(H2,9,11). InChi Key: AEOCXXJPGCBFJA-UHFFFAOYSA-N.