Erythromycin lactobionate

Erythromycin lactobionate is a macrolide antibiotic and water-soluble form of erythromycin (Cay-16486). It is active against S. aureus and S. pneumoniae, as well as clinical isolates of group A streptococci (MICs = 0.6, 0.06, and 0.031 µg/ml, respectively). Erythromycin lactobionate (50 mg/kg) increases survival and reduces the number of lung colony forming units (CFUs) in a mouse model of S. pneumoniae-induced pneumonia. It also increases survival in mice infected with P. aeruginosa when administered at doses of 50 and 100 mg/kg. Formulations containing erythromycin lactobionate have been used in the treatment of various Gram-positive and Gram-negative bacterial infections.Formal Name: 4-O-beta-D-galactopyranosyl-D-gluconate erythromycin. CAS Number: 3847-29-8. Molecular Formula: C37H67NO13 . C12H22O12. Formula Weight: 1092.2. Formulation: (Request formulation change), A crystalline solid. Solubility: Water: 1 mg/ml. SMILES: C[C@H]1[C@H](O)[C@@](OC)(C)C[C@@](O[C@H]([C@@H](C)C(O[C@H](CC)[C@]([C@H](O)[C@H]2C)(O)C)=O)[C@H](C)[C@@H](O[C@@]3([H])[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3)[C@](C)(O)C[C@@H](C)C2=O)([H])O1.O[C@@H]4[C@H](O)[C@@H](O)[C@H](O[C@]([C@H](O)[C@@H](O)C(O)=O)([H])[C@H](O)CO)O[C@@H]4CO. InChi Code: InChI=1S/C37H67NO13.C12H22O12/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26,13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/. InChi Key: NNRXCKZMQLFUPL-WBMZRJHASA-N.