Avilamycin A

Avilamycin A is an antibiotic. It is active against veterinary isolates of C. perfringens (MICs = =0.06-0.5 mg/L) and B. hyodysenteriae (MICs = 12.5-100 µg/ml). Dietary administration of avilamycin A (15 and 30 ppm) reduces mortality in a broiler cockerel model of C. perfringens infection. Formulations containing avilamycin A have been used in the prevention of necrotic enteritis in livestock.Formal Name: O-(1R)-4-C-acetyl-6-deoxy-2,3-O-methylene-D-galactopyranosylidene-(1->3-4)-2-O-(2-methyl-1-oxopropyl)-alpha-L-lyxopyranosyl O-2,6-dideoxy-4-O-(3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoyl)-beta-D-arabino-hexopyranosyl-(1->4)-O-2,6-dideoxy-D-arabino-hexopyranosylidene-(1->3-4)-O-2,6-dideoxy-3-C-methyl-beta-D-arabino-hexopyranosyl-(1->3)-O-6-deoxy-4-O-methyl-beta-D-galactopyranosyl-(1->4)-2,6-di-O-methyl-beta-D-mannopyranoside. CAS Number: 69787-79-7. Molecular Formula: C61H88Cl2O32. Formula Weight: 1404.2. Purity: >75%. Formulation: (Request formulation change), A solid. Solubility: Acetone: slightly soluble, Methanol: slightly, heated. SMILES: C[C@@H]1[C@@H](OC(C2=C(C)C(Cl)=C(O)C(Cl)=C2OC)=O)[C@H](O)C[C@H](O[C@@H]3[C@@H](C)OC4(O[C@@H]5[C@@H](C)O[C@@H](O[C@@H]6[C@@H](O)[C@H](O[C@@H]7[C@@H](COC)O[C@@H](OC8[C@H](OC(C(C)C)=O)[C@H]9[C@@H](O[C@]%10([C@H]%11[C@@H](OCO%11)[C@@](C(C)=O)(O)[C@@H](C)O%10)O9)CO8)[C@@H](OC)[C@H]7O)O[C@H](C)[C@@H]6OC)C[C@@]5(C)O4)C[C@H]3O)O1. InChi Code: InChI=1S/C61H88Cl2O32/c1-21(2)53(70)87-49-45-32(92-61(93-45)52-51(78-20-79-52)60(72,27(8)64)28(9)91-61)19-77-56(49)89-57-48(76-14)39(68)44(31(83-57)18-73-11)88-55-40(69)47(43(74-12)24(5)82-55)85-34-17-58(10)50(26(7)81-34)94-59(95-58)16-30(66)42(25(6)90-59)84-33-15-29(65)41(23(4)80-33)86-54(71)35-22(3)36(62)38(67)37(63)46(35)75-13/h21,23-26,28-34,39-45,47-52,55-57,65-69,72H,15-20H2,1-14H3/t23-,24-,25-,26-,28-,29-,30-,31-,32+,33+,34+,39+,40-,41-,42-,43+,44-,45-,47-,48+,49-,50-,51-,52-,55+,56?,57+,58-,59?,60+,61-/m1/s1. InChi Key: XIRGHRXBGGPPKY-OTPQUNEMSA-N.