Apramycin (sulfate hydrate)

Apramycin is an aminoglycoside antibiotic first isolated from S. tenebrarius. It is active against a variety of Gram-positive and Gram-negative bacteria, including strains which produce aminoglycoside-modifying enzymes. Apramycin inhibits protein synthesis in bacteria both in vivo and in vitro.Formal Name: O-4-amino-4-deoxy-alpha-D-glucopyranosyl-(1->8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-alpha-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1->4)-2-deoxy-D-streptamine, sulfate, hydrate. Synonyms: Nebramycin II. Molecular Formula: C21H41N5O11 . XH2SO4 [XH2O]. Formula Weight: 539.6. Purity: >95%. Formulation: (Request formulation change), A powder. Solubility: PBS (pH 7.2): 10 mg/mL. SMILES: OC[C@H]([C@@H](N)[C@H](O)[C@H]1O)O[C@]1([H])O[C@@H]2[C@@H](NC)[C@@H](O)[C@@]3([H])O[C@H](O[C@@]4([H])[C@H](O)[C@@H](O)[C@H](N)C[C@@H]4N)[C@H](N)C[C@]3([H])O2.OS(O)(=O)=O.O. InChi Code: InChI=1S/C21H41N5O11.H2O4S.H2O/c1-26-11-14(30)18-8(33-20(11)37-21-16(32)13(29)10(25)9(4-27)34-21)3-7(24)19(36-18)35-17-6(23)2-5(22)12(28)15(17)31,1-5(2,3)4,/h5-21,26-32H,2-4,22-25H2,1H3,(H2,1,2,3,4),1H2/t5-,6+,7-,8+,9-,10-,11+,12+,13+,14-,15-,16-,17-,18+,19+,20-,21-,,/m1../s1. InChi Key: QZMYGUIMDGWSNW-PWWORVPNSA-N.