regulated on activation in normal T-cell expressed and secreted, RANTES (mouse) ELISA Kit

Sample Types: serum, plasma, tissue homogenates. Detection Range: 7.8 pg/mL-500 pg/mL. Sensitivity: 3.9 pg/mL. Assay Principle: quantitative. Measurement: Sandwich. Assay Time: 1-5h. Sample Volume: 50-100ul. Detection Wavelength: 450 nm. Protein function: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. [The UniProt Consortium]