Artikelnummer | Größe | Datenblatt | Manual | SDB | Lieferzeit | Menge | Preis |
---|---|---|---|---|---|---|---|
227841.48 | 48 tests | - | - |
3 - 19 Werktage* |
768,00 €
|
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227841.96 | 96 tests | - | - |
3 - 19 Werktage* |
958,00 €
|
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Protein function: Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5- DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, induci
Schlagworte: | p25, HNL, NGAL, LCN2, Lipocalin-2, Oncogene 24p3, Siderocalin LCN2, Neutrophil gelatinase-associated lipocalin, 25 kDa alpha-2-microglobulin-related subunit of MMP-9 |
Hersteller: | United States Biological |
Hersteller-Nr: | 227841 |
Eigenschaften
Anwendung: | ELISA |
Format: | Solid Phase |
Datenbank Information
KEGG ID : | K21129 | Passende Produkte |
UniProt ID : | P80188 | Passende Produkte |
Gene ID : | GeneID 3934 | Passende Produkte |
Handhabung & Sicherheit
Lagerung: | +4°C |
Versand: | +4°C (International: +4°C) |
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!