Mouse PPAR-gamma (Peroxisome Proliferator Activated Receptor Gamma) ELISA Kit

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of PPAR-gamma in serum, plasma and other biological fluids. Detection Range: 0.16--10ng/mL. Sensitivity: 0.1ng/mL. Protein function: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels (PubMed:19041764). [The UniProt Consortium]