Human MUC4 (Mucin 4) ELISA Kit

Human MUC4 (Mucin 4) ELISA Kit
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-HUES01866.96 96 assays -

9 - 20 Werktage*

641,00 €
 
ELISA Type: Sandwich. Sensitivity: 0.188ng/mL. Range: 0.313--20ng/mL. Protein function: May play... mehr
Produktinformationen "Human MUC4 (Mucin 4) ELISA Kit"
ELISA Type: Sandwich. Sensitivity: 0.188ng/mL. Range: 0.313--20ng/mL. Protein function: May play a role in tumor progression. Ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation. Has anti-adhesive properties. Seems to alter cellular behavior through both anti-adhesive effects on cell-cell and cell- extracellular matrix interactions and in its ability to act as an intramembrane ligand for ERBB2. Plays an important role in cell proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2. The MUC4-ERBB2 complex causes site- specific phosphorylation of the ERBB2 'Tyr-1248'. In polarized epithelial cells segregates ERBB2 and other ERBB receptors and prevents ERBB2 from acting as a coreceptor. The interaction with ERBB2 leads to enhanced expression of CDKN1B. The formation of a MUC4-ERBB2-ERBB3-NRG1 complex leads to down-regulation of CDKN1B, resulting in repression of apoptosis and stimulation of proliferation. [The UniProt Consortium]
Schlagworte: MUC4
Hersteller: Assay Genie
Hersteller-Nr: HUES01866

Eigenschaften

Anwendung: Sandwich ELISA
Spezies-Reaktivität: human
Format: Solid Phase

Handhabung & Sicherheit

Lagerung: vT
Versand: +4°C (International: +4°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H315, H319
P-Sätze: P264, P280
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Human MUC4 (Mucin 4) ELISA Kit"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen