CCL2 (pig) ELISA Kit

CCL2 also known as the monocyte chemoattractant protein-1 (MCP-1) is a chemokine and more particularly an C-C chemokine. Initially discovered in 1983, it is a monomeric polypeptide of 73 amino acids (13 kDa). It belongs to a family composed at least of members (MCP-1, -2, -3, and -4). CCL-2 is produced by the immune-cells (monocyte/macrophages) and non-immune cells (endothelial cells-fibroblast-myocyte). The main function of the CCL2 is the chimiotactism and more particularly the regulation of the migration and the infiltration of monocytes, memory T lymphocytes, and natural killer (NK) cells on an infection site. CCL2 is involved in many diseases like HIV-1 pathogenesis, cancer, cardiovascular disease, or diabetes. [Bertin Catalog No. A05415]Synonyms: CCL2 EIA Kit, Chemokine (C-C Motif) Ligand 2, GDCF-2 HC11, HSMCR30, MCAF, MCP-1, MGC9434, Monocyte Chemotactic Protein 1, Monocyte Secretory Protein JE, SCYA2, Small-Inducible Cytokine A2. Limit of Detection: =3.8 pg/ml. Assay Range: 3,8-500,0 pg/ml. Cross Reactivity: (+++) Recombinant CCL2 (bovine), (+++) Recombinant CCL2 (equine), (+++) Recombinant CCL2 (canine), (+/-) Recombinant CCL2 (guinea pig), (+/-) Recombinant CCL2 (mouse), (-) Recombinant CCL2 (rabbit).