Bovine CD14 (Monocyte differentiation antigen CD14) ELISA Kit (BOFI00129)

Bovine CD14 (Monocyte differentiation antigen CD14) ELISA Kit from Assay Genie is a pre-coated immunoassay with a high sensitivity and broad range and has been designed to measure Bovine CD14 (Monocyte differentiation antigen CD14) in serum, plasma & cell culture supernatant samples. The Bovine CD14 (Monocyte differentiation antigen CD14) ELISA Kit accurately measures natural Bovine CD14 (Monocyte differentiation antigen CD14) levels quantified versus standard curves obtained and is based on antibodies raised against a recombinant Bovine CD14 (Monocyte differentiation antigen CD14) peptide. Protein function: Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-). [The UniProt Consortium]