Anti-phospho-JAK2 (Tyr372)

Anti-JAK II was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with human, orangutan, rat, and pig based on 100% sequence homology. Cross-reactivity with JAK II from other sources has not been determined. Janus Kinase 2 (JAK2) antibody is essential for signaling thorough a variety of cytokine receptors. Phosphorylation of JAK is essential for downstream signaling. JAK kinases are known to phosphorylate several substrate including members of the STAT family of proteins. Anti-JAK II antibody is ideal for researchers investigating Cancer, Signal Transduction, Epigenetics and Nuclear Signaling, and Cell Biology research.