Anti-phospho-IkB- Alpha (Tyr42) Antibody

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-35-1155-50 50 µl -

3 - 11 Werktage*

574,00 €
 
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm... mehr
Produktinformationen "Anti-phospho-IkB- Alpha (Tyr42) Antibody"
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription. Protein function: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. [The UniProt Consortium]
Schlagworte: Anti-phospho-IKBA, Anti-phospho-NFKBIA, Anti-phospho-IkB-alpha, Anti-phospho-IkappaBalpha, Anti-phospho-I-kappa-B-alpha, Anti-phospho-NF-kappa-B inhibitor alpha, Anti-phospho-Major histocompatibility complex enhancer-binding protein MAD3, Polyclonal Antib
Hersteller: Abeomics
Hersteller-Nr: 35-1155-50

Eigenschaften

Anwendung: WB, IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
Immunogen: Peptide sequence around phosphorylation site of tyrosine 42 (E-E-Y(p)-E-Q) derived from Human IkB-a
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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