Anti-UchL1, clone SPM575

Anti-UchL1, clone SPM575
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-V9097-20UG 20 µg - -

3 - 10 Werktage*

332,00 €
NSJ-V9097-100UG 100 µg - -

3 - 10 Werktage*

752,00 €
 
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. This mAb reacts with a protein of... mehr
Produktinformationen "Anti-UchL1, clone SPM575"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. This mAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, UchL1 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for UchL1 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in the gene is believed to cause a form of Parkinson's disease. Protein function: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity. [The UniProt Consortium]
Schlagworte: Anti-UCHL1, Anti-PGP9.5, Anti-UCH-L1, Anti-PGP 9.5, EC=6.-.-.-, EC=3.4.19.12, Anti-Ubiquitin thioesterase L1, Anti-Neuron cytoplasmic protein 9.5, Anti-Ubiquitin carboxyl-terminal hydrolase isozyme L1, Anti-UchL1 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: V9097

Eigenschaften

Anwendung: WB, IF
Antikörper-Typ: Monoclonal
Klon: SPM575
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human, bovine, dog, guinea swine, , mouse, swine, rabbit, rat, sheep, zebrafish
Immunogen: Native UchL1/PGP9.5 protein isolated from human brain was used as the immunogen for this anti-UchL1 antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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