Artikelnummer | Größe | Datenblatt | Manual | SDB | Lieferzeit | Menge | Preis |
---|---|---|---|---|---|---|---|
ABE-44-1097-1 | 1 ml | - |
3 - 11 Werktage* |
1.449,00 €
|
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SRY (Sex Determining Region Y)-Box 11 (SOX-11), also known as transcription factor SOX-11, is a nuclear transcription factor that acts in regulation of embryonic development and in cell differentiation. SOX-11 is expressed in the development of the human central nervous system, medulloblastoma, and glioma, and has been indicated as a marker for both Cyclin D1-positive and negative mantle cell lymphomas, Burkitt lymphoma, and lymphoblastic lymphoma. Protein function: Transcription factor that acts as a transcriptional activator (PubMed:24886874). Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation. Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron. Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis. [The UniProt Consortium]
Schlagworte: | Anti-SOX11, Anti-Transcription factor SOX-11, Anti-SOX-11 Monoclonal Antibody (Clone:IHC011) |
Hersteller: | Abeomics |
Hersteller-Nr: | 44-1097 |
Eigenschaften
Anwendung: | IHC |
Antikörper-Typ: | Monoclonal |
Klon: | IHC011 |
Konjugat: | No |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
Format: | Purified |
Datenbank Information
KEGG ID : | K09268 | Passende Produkte |
UniProt ID : | P35716 | Passende Produkte |
Gene ID : | GeneID 6664 | Passende Produkte |
Handhabung & Sicherheit
Lagerung: | -20°C |
Versand: | +4°C (International: +4°C) |
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!