Anti-Soluble Epoxide Hydrolase

Anti-Soluble Epoxide Hydrolase
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10010146-1 1 each -

6 - 10 Werktage*

431,00 €
 
Soluble epoxide hydrolase (sEH) is a member of the alpha/beta-hydrolase fold enzyme family that... mehr
Produktinformationen "Anti-Soluble Epoxide Hydrolase"
Soluble epoxide hydrolase (sEH) is a member of the alpha/beta-hydrolase fold enzyme family that catalyzes the hydrolysis of bioactive fatty acid epoxides to inactive vicinal diols. It is a homodimer in which each subunit is composed of two domains, a C-terminal epoxide hydrolase domain and an N-terminal phosphatase domain. sEH is localized to the cytoplasm or to peroxisomes in a tissue-specific manner and is found in various tissues, including skin, lung, uterus, kidney, brain, and myocardium. sEH is also expressed in the vasculature and inhibition of sEH attenuates pathogenic vascular remodeling and hypertension via preservation of cardioprotective epoxyeicosatrienoic acids (EETs) in rat models of atherosclerosis and hypertension, respectively. Inhibition of sEH also has a protective role in various diseases, including inflammatory bowel disease, osteoarthritis, seizure, stroke, and Alzheimer's disease, as well as in various chronic pain states. Cayman's Soluble Epoxide Hydrolase Polyclonal Antibody can be used for Western blot. The antibody recognizes sEH at approximately 64 kDa from human, mouse, and rat samples.Synonyms: Cytosolic Epoxide Hydrolase (CEH), EPHX2, Epoxide Hydrolase 2, sEH. Immunogen: Synthetic peptide from the internal region of human sEM. Formulation: (Request formulation change), 500 µl of peptide affinity-purified polyclonal antibody. Storage Buffer: PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide. Host: Rabbit. Applications: WB. UniProt Accession #: P34913. Origin: Animal/Rabbit.
Schlagworte: Anti-CEH, Anti-CEH, Anti-Epoxide hydratase, Anti-Epoxide hydratase, Anti-Lipid-phosphate phosphatase, Anti-Lipid-phosphate phosphatase, Anti-Cytosolic epoxide hydrolase 2, Anti-Cytosolic epoxide hydrolase 2, Anti-Bifunctional epoxide hydrolase 2 {ECO:0000
Hersteller: Cayman Chemical
Hersteller-Nr: 10010146

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, murine, rat (Erwartet: bovine, swine, canine, chicken)
Immunogen: Synthetic peptide from the internal region of human sEM
Format: Solid

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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