Anti-SMS

This gene encodes a protein belonging to the spermidine/spermin synthase family. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene are associated with X-linked Snyder-Robinson mental retardation syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Protein function: Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM). [The UniProt Consortium]