Anti-PSMB6

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA023312.25 25 µl -

7 - 10 Werktage*

358,00 €
ATA-HPA023312.100 100 µl -

7 - 10 Werktage*

477,00 €
 
Protein function: Component of the 20S core proteasome complex involved in the proteolytic... mehr
Produktinformationen "Anti-PSMB6"
Protein function: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin- independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB6 displays a peptidylglutamyl-hydrolizing activity also termed postacidic or caspase-like activity, meaning that the peptides bond hydrolysis occurs directly after acidic residues. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 84% and to rat: 86%
Schlagworte: Anti-LMPY, Anti-PSMB6, Anti-Proteasome subunit Y, Anti-Macropain delta chain, Anti-Proteasome delta chain, Anti-Proteasome subunit beta type-6, Anti-Multicatalytic endopeptidase complex delta chain
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA023312

Eigenschaften

Anwendung: IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: MAATLLAARG AGPAPAWGPE AFTPDWESRE VSTGTTIMAV QFDGGVVLGA DSRTTTGSYI ANRVTDKLT (ATA-APrEST75729)

Datenbank Information

KEGG ID : K02738 | Passende Produkte
UniProt ID : P28072 | Passende Produkte
Gene ID : GeneID 5694 | Passende Produkte
Protein Atlas Nr. : ENSG00000142507

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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