Anti-PSD-95

Anti-PSD-95 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. This antibody is directed against PSD 95 proteins. Reactivity is expected from the following species based on 100% sequence homology: bovine, human, mouse, non-human primates and zebra fish. Protein function: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. [The UniProt Consortium]