Anti-PPP1CB

Anti-PPP1CB
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG40114.100 100 µl - -

6 - 14 Werktage*

616,00 €
 
Protein function: Protein phosphatase that associates with over 200 regulatory proteins to form... mehr
Produktinformationen "Anti-PPP1CB"
Protein function: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T- cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208). [The UniProt Consortium]
Schlagworte: Anti-PP-1B, Anti-PPP1CD, Anti-PPP1CB, EC=3.1.3.16, EC=3.1.3.53, Anti-Serine/threonine-protein phosphatase PP1-beta catalytic subunit
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG40114

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat (Erwartet: bovine, chicken, swine, rabbit, Xenopus)
Immunogen: KLH-conjugated synthetic peptide corresponding to aa. 298-327 of Human PPP1CB
MW: 37 kD
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: °C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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