Anti-Phosphoinositide-3 Kinase (PI3K), p110 delta

Phosphoinositide 3 kinase (PI3K) enzymes regulate signal transduction through intricate feedback and cross-talk pathways. PI3K has a catalytic subunit and a regulatory subunit. Mammals have three Class 1A isoforms of the catalytic subunit are known as p110alpha, p110beta, and p110delta and one class IB subunit known as p110gamma. The p110delta catalytic subunit is restricted to lymphocytes and some cells of breast and melanocytic origin. Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000, Immunohistochemistry: Paraffin sections, Immunocytochemistry: 1:300, Optimal dilutions to be determined by the researcher. Positive Control: Human T cell line Jurkat, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.