Anti-PGP9.5, clone SPM574

Anti-PGP9.5, clone SPM574
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-V9096SAF-100UG 100 µg - -

3 - 10 Werktage*

752,00 €
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. This mAb reacts with a protein of 20-30kDa,... mehr
Produktinformationen "Anti-PGP9.5, clone SPM574"
1 mg/ml in sterile PBS, BSA free, sodium azide free. This mAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease. Protein function: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity. [The UniProt Consortium]
Schlagworte: Anti-UCHL1, Anti-PGP9.5, Anti-UCH-L1, Anti-PGP 9.5, EC=6.-.-.-, EC=3.4.19.12, Anti-Ubiquitin thioesterase L1, Anti-Neuron cytoplasmic protein 9.5, Anti-Ubiquitin carboxyl-terminal hydrolase isozyme L1, Anti-PGP9.5 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: V9096SAF

Eigenschaften

Anwendung: WB, IHC
Antikörper-Typ: Monoclonal
Klon: SPM574
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human, mouse, rat, bovine, swine
Immunogen: Native UchL1/PGP9.5 protein isolated from human brain was used as the immunogen for this anti-PGP9.5 antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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