Anti-PDL1

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
600-101-GU8S 25 µl - -

6 - 10 Werktage*

180,00 €
 
This affinity purified antibody is directed against human PDL1. This product was affinity... mehr
Produktinformationen "Anti-PDL1"
This affinity purified antibody is directed against human PDL1. This product was affinity purified from monospecific antiserum by immunoaffinity purification. Blast analysis of the sequence of the immunogen shows 100% identity with human. Protein function: Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (PubMed:28813417, PubMed:28813410). Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077). [The UniProt Consortium]
Schlagworte: Anti-B7H1, Anti-CD274, Anti-B7-H1, Anti-PD-L1, Anti-B7 homolog 1, Anti-PDCD1 ligand 1, Anti-Programmed death ligand 1, Anti-Programmed cell death 1 ligand 1
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 600-101-GU8S

Eigenschaften

Anwendung: ELISA, FC, IHC, IFM, IP, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Goat
Spezies-Reaktivität: human, mouse
Immunogen: synthetic peptide corresponding to an internal portion of human PDL1 conjugated to Keyhole Limpet Hemocyanin (KLH).
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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