Anti-PD-1 Monoclonal Antibody (Clone:IHC001)-Ready to Use

Anti-PD-1 Monoclonal Antibody (Clone:IHC001)-Ready to Use
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-44-1068-7 7 ml -

3 - 11 Werktage*

672,00 €
 
Programmed Death 1 (PD-1) is a member of the CD28/CTLA-4 family of T-cell regulators, expressed... mehr
Produktinformationen "Anti-PD-1 Monoclonal Antibody (Clone:IHC001)-Ready to Use"
Programmed Death 1 (PD-1) is a member of the CD28/CTLA-4 family of T-cell regulators, expressed as a co-receptor on the surface of activated T-cells, B-cells, and macrophages. New studies have suggested that the PD-1/PD-L1 signaling pathway may be linked to anti-tumor immunity, as PD-L1 has been shown to induce apoptosis of activated T cells or inhibit activity of cytotoxic T cells. In comparison to CD10 and Bcl-6, PD-1 is expressed by fewer B cells and has therefore been considered a more specific marker for angioimmunoblastic T-cell lymphoma. Therapies targeted toward the PD-1 receptor have shown remarkable clinical responses in patients with various types of cancer, including non-small-cell lung cancer, melanoma, and renal-cell cancer. Protein function: Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors. [The UniProt Consortium]
Schlagworte: Anti-PD1, Anti-hPD-1, Anti-PDCD1, Anti-CD279, Anti-Protein PD-1, Anti-Programmed cell death protein 1, Anti-PD-1 Monoclonal Antibody (Clone:IHC001)-Ready to Use
Hersteller: Abeomics
Hersteller-Nr: 44-1068-7

Eigenschaften

Anwendung: ELISA, IHC
Antikörper-Typ: Monoclonal
Klon: IHC001
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: Recombinant human His-PD1

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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