Anti-p27Kip1, clone KIP27-1

Anti-p27Kip1, clone KIP27-1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-V7048IHC-7ML 7 ml - -

3 - 10 Werktage*

752,00 €
 
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. This... mehr
Produktinformationen "Anti-p27Kip1, clone KIP27-1"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. This mAb recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. Protein function: Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1- CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. [The UniProt Consortium]
Schlagworte: Anti-KIP1, Anti-CDKN1B, Anti-p27Kip1, Anti-Cyclin-dependent kinase inhibitor 1B, Anti-Cyclin-dependent kinase inhibitor p27, p27Kip1 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: V7048IHC

Eigenschaften

Anwendung: IHC
Antikörper-Typ: Monoclonal
Klon: KIP27-1
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human, mouse, rat
Immunogen: Recombinant human protein was used as the immunogen for the p27Kip1 antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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