Anti-Nampt (Visfatin/PBEF) (human)

Recognizes human Nampt. Weakly cross-reacts with mouse Nampt. Detects a band of about 54kDa by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Nampt also known as pre-B cell colony-enhancing factor 1 (PBEF1) or visfatin is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.