Anti-Mouse CD122 NALE(TM) Purified (Clone: TM-beta1)

The TM-beta1 monoclonal antibody specifically reacts with mouse CD122, a beta chain shared by the IL-2 and IL-15 receptors. It is expressed by B cells, T cells, and NK cells and can be used as a marker for NK-cell progenitors. CD122 forms complexes involved in immunoregulation and signal transduction. The TM-beta1 antibody is reported to block the binding of IL-2 and IL-15 to the IL-2 beta receptor. Protein function: Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. [The UniProt Consortium]