Anti-LAG-3, blocking, clone 11E3

Recognizes human and monkey LAG-3. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function, and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell coreceptor CD4, and binds to MHC class II molecules but with a significantly higher affinity than CD4.