Anti-KIAA1324

Expression of this gene is induced by estrogen and the encoded protein has been characterized as a transmembrane protein. The encoded protein has been found in to correlate with survival in certain carcinomas (PMID: 21102415) and may be important for cellular response to stress (PMID: 21072319). Alternative splicing results in multiple transcript variants. Protein function: May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway. [The UniProt Consortium]