Anti-JAG2

The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development. [The UniProt Consortium]