Sichern Sie sich 30% Rabatt auf alle Primärantikörper von Arigo Biolaboratories!
*1Artikelnummer | Größe | Datenblatt | Manual | SDB | Lieferzeit | Menge | Rabatt | Preis |
---|---|---|---|---|---|---|---|---|
ARG66320.100 | 100 µl | - | - |
6 - 14 Werktage* |
30 %
|
624,00 €
436,80 € |
Bestellen Sie auch per E-Mail: info@biomol.com
Größere Menge gewünscht? Bulk-Anfrage
Protein function: Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'- linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B- mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response, this function requires 'Lys-27'-linked polyubiquitination. [The UniProt Consortium]
Schlagworte: | Anti-NEMO, Anti-IKKG, Anti-FIP3, Anti-IKBKG, Anti-FIP-3, Anti-IKKAP1, Anti-IKK-gamma, Anti-IkB kinase subunit gamma, Anti-NF-kappa-B essential modifier, Anti-NF-kappa-B essential modulator, Anti-I-kappa-B kinase subunit gamma |
Hersteller: | Arigo Biolaboratories |
Hersteller-Nr: | ARG66320 |
Eigenschaften
Anwendung: | FC, IHC (paraffin), IP, WB |
Antikörper-Typ: | Monoclonal |
Klon: | SQab1868 |
Konjugat: | No |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
Immunogen: | Synthetic peptide around the N-terminus of IKK gamma |
MW: | 48 kD |
Format: | Purified |
Datenbank Information
KEGG ID : | K07210 | Passende Produkte |
UniProt ID : | Q9Y6K9 | Passende Produkte |
Gene ID | GeneID 8517 | Passende Produkte |
Handhabung & Sicherheit
Lagerung: | -20°C |
Versand: | +4°C (International: +4°C) |
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!