Anti-FOXP3 (human), clone ANCFX2D7 (R-PE)

Monoclonal Antibody. Recognizes human FOXP3. Isotype: Mouse IgG1kappa. Clone: ANCFX2D7. Applications: ELISA, FACS. 50mM Sodium phosphate pH7.5, 100mM Potassium chloride, 150mM NaCl, 5% glycerol, 0.2%BSA, 0.04% sodium azide (preservative). FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.