Anti-DAAM1

In 1X PBS, pH 7.4, with 0.09% sodium azide. Disheveled-associated activator of morphogenesis 1 binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. [UniProt] Protein function: Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia (PubMed:16630611, PubMed:17482208). Involved in the organization of the subapical actin network in multiciliated epithelial cells. Together with DAAM2, required for myocardial maturation and sarcomere assembly. [The UniProt Consortium]