Anti-CHP2

Polyclonal Antibody against Human CHP2, Gene description: calcineurin like EF-hand protein 2, Validated applications: ICC, Uniprot ID: O43745, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus. [The UniProt Consortium] Mouse gene identity: 77% Rat gene identity: 77%