Anti-CD63, clone CDLA63-1

Anti-CD63, clone CDLA63-1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-V7190IHC-7ML 7 ml - -

3 - 10 Werktage*

752,00 €
 
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. CD63... mehr
Produktinformationen "Anti-CD63, clone CDLA63-1"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. CD63 functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. [UniProt] Protein function: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. [The UniProt Consortium]
Schlagworte: Anti-CD63, Anti-MLA1, Anti-OMA81H, Anti-LAMP-3, Anti-Tspan-30, Anti-CD63 antigen, Anti-Granulophysin, Anti-Tetraspanin-30, Anti-Melanoma-associated antigen ME491, Anti-Ocular melanoma-associated antigen, Anti-Lysosomal-associated membrane protein 3, CD63
Hersteller: NSJ Bioreagents
Hersteller-Nr: V7190IHC

Eigenschaften

Anwendung: IHC
Antikörper-Typ: Monoclonal
Klon: CDLA63-1
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: Recombinant human full-length protein was used as the immunogen for the CD63 antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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