Anti-CD102

Predicted to enable integrin binding activity. Predicted to be involved in cell adhesion. Located in microvillus, plasma membrane, and uropod. Is integral component of plasma membrane. Is expressed in central nervous system, extraembryonic component, female reproductive system, retina, and vascular element. Orthologous to human ICAM2 (intercellular adhesion molecule 2). Protein function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. [The UniProt Consortium]