Anti-CCL5 (canine)

The Canine CCL5 polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Biotech Canine CCL5 ELISA. The Canine CCL5 antibody was produced in rabbits and is antigen-affinity purified. The reactivity by species is: (Canine CCL5 - Strong) (Bovine CCL5 - None) (Chicken CCL5 - None) (Cynomolgus monkey CCL5 - None) (Dolphin CCL5 - None) (Equine CCL5 - None) (Feline CCL5 - None) (Ferret CCL5 - None) (Guinea pig CCL5 - None) (Hamster CCL5 - None) (Human CCL5 - None) (Mouse CCL5 - None) (Ovine CCL5 - None) (Rabbit CCL5 - None) (Swine CCL5 - None) (Turkey CCL5 - None). For research use only. Made in the USA Protein function: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. [The UniProt Consortium]