Anti-CB2

In 1X PBS, pH 7.4, with 0.09% sodium azide. The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. Cannabinoid receptor 2 and cannabinoid receptor 1 (brain) (CNR1) have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. Protein function: Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis. [The UniProt Consortium]