Anti-Caspase 2 (Caspase-2 Apoptosis-related Cysteine Protease, CASP 2, CASP2, CASP-2, ICH 1, ICH1, I

Caspase 2 is a member of the cysteine-aspartic acid protease (caspase) family and acts as both a positive and negative regulator of apoptosis. Overexpression of the full length Caspase 2 (Isoform ICH-1L) in some cell types results in apoptosis whereas the overexpression of an alternative Caspase 2 (ICH-1S) splice variant suppresses apoptosis. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. , Recommended Dilution: Western Blot: 0.5-1ug/ml, Immunohistochemistry (Paraffin and Formalin): 1-2.0ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.