Anti-CACNA1D

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-16291.20 20 µl -

7 - 16 Werktage*

71,00 €
E-AB-16291.60 60 µl -

7 - 16 Werktage*

143,00 €
E-AB-16291.120 120 µl -

7 - 16 Werktage*

238,00 €
E-AB-16291.200 200 µl -

7 - 16 Werktage*

396,00 €
 
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and... mehr
Produktinformationen "Anti-CACNA1D"
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. Protein function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin- GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). [The UniProt Consortium]
Schlagworte: Anti-CACH3, Anti-CACNA1D, Anti-Voltage-gated calcium channel subunit alpha Cav1.3, Anti-Calcium channel, L type, alpha-1 polypeptide, isoform 2, Anti-Voltage-dependent L-type calcium channel subunit alpha-1D, CACNA1D Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-16291

Eigenschaften

Anwendung: IHC, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, rat
Immunogen: Synthetic peptide of human CACNA1D
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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