Anti-Beta-2 Microglobulin, clone MGBP2-2R

1 mg/ml in 1X PBS, BSA free, sodium azide free. Beta-2 Microglobulin/B2M is a component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [UniProt] Protein function: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553). [The UniProt Consortium]