Anti-Beta-2 Microglobulin, clone C21.48A1

Anti-Beta-2 Microglobulin, clone C21.48A1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-V2803SAF-100UG 100 µg - -

3 - 10 Werktage*

752,00 €
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. The antibody recognizes the hidden... mehr
Produktinformationen "Anti-Beta-2 Microglobulin, clone C21.48A1"
1 mg/ml in sterile PBS, BSA free, sodium azide free. The antibody recognizes the hidden determinant of beta-2 microglobulin (i.e. binding to its determinant is available only when the chain is separated from the HLA heavy chain). Beta-2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta-2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta-2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy). Protein function: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [The UniProt Consortium]
Schlagworte: Anti-B2M, Anti-CDABP0092, Beta-2 Microglobulin Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: V2803SAF

Eigenschaften

Anwendung: FC, IF
Antikörper-Typ: Monoclonal
Klon: C21.48A1
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human, primates
Immunogen: Soluble beta 2 microglobulin
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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