Anti-Beta-2 Microglobulin, clone BBM.1

Anti-Beta-2 Microglobulin, clone BBM.1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-V2802-20UG 20 µg - -

3 - 10 Werktage*

332,00 €
NSJ-V2802-100UG 100 µg - -

3 - 10 Werktage*

752,00 €
 
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Recognizes a protein of 12kDa,... mehr
Produktinformationen "Anti-Beta-2 Microglobulin, clone BBM.1"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Recognizes a protein of 12kDa, identified as microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha- heavy chain that contains three subdomains (alpha-1, alpha-2, alpha-3) and a non-covalent associating light chain, known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha-3 subdomain of the alpha- heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha-1 and alpha-2 domains of the alpha- heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes. Protein function: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [The UniProt Consortium]
Schlagworte: Anti-B2M, Anti-CDABP0092, Beta-2 Microglobulin Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: V2802

Eigenschaften

Anwendung: FC, IF, IF, IP
Antikörper-Typ: Monoclonal
Klon: BBM.1
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human, primates
Immunogen: MOLT-4 cell line
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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