Anti-BACE

Anti-BACE
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-F50757-0.08ML 80 µl - -

3 - 10 Werktage*

350,00 €
NSJ-F50757-0.4ML 400 µl - -

3 - 10 Werktage*

755,00 €
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. Cerebral deposition of amyloid beta peptide is an... mehr
Produktinformationen "Anti-BACE"
In 1X PBS, pH 7.4, with 0.09% sodium azide. Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Protein function: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. [The UniProt Consortium]
Schlagworte: Anti-ASP2, Anti-BACE, Anti-Asp 2, Anti-BACE1, Anti-Memapsin-2, EC=3.4.23.46, Anti-Beta-secretase 1, Anti-Aspartyl protease 2, Anti-Beta-site APP cleaving enzyme 1, Anti-Membrane-associated aspartic protease 2, BACE Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: F50757

Eigenschaften

Anwendung: WB, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
Immunogen: A portion of amino acids 476-501 from the human protein was used as the immunogen for this BACE antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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