Anti-AMACR (human), Rabbit Monoclonal (RM349)

Recombinant Antibody. This antibody reacts to human p504s/AMACR. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Alpha-methylacyl-CoA racemase (AMACR), also known as p504s, is a mitochondrial and peroxisomal enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. p504s is essential in lipid metabolism, and is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). Expression is granular and cytoplasmic. p504s expression can also be found in hepatocellular carcinoma, kidney carcinoma and in various colon carcinomas and is overexpressed in prostate carcinoma.