Anti-Alpha-Tubulin, clone TU-02 (Monoclonal) [Mouse]

MON 4018 reacts with the N-terminal domain of alpha-tubu lin. Tubulin isotypes have been identified with tissue specific expression. Immunocytochem ical studies using several mAbs revealed remarkable heterogeneity of tubulin within various nervous tissues. It reacts with tubulin in fixed tissues only, not in unfixed or li ve tissues or cells. Interphase microtubules are also stained by TU-02 in fixed tissues. Immunoge n : microtubular protein f rom pig brain Protein function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [The UniProt Consortium]