Anti-Ah Receptor (Aryl Hydrocarbon Receptor)

The Ah Receptor belongs to a family of proteins comprised of its dimerization partner ARNT (HIF-1 Beta) and the Drosophila proteins PER and SIM. All of these proteins share an N-terminal sequence of ~200aa termed the PAS domain. This receptor, found in a variety of tissues, binds to a specific DNA enhancer sequence and initiates transcription of the mRNA for the cytochrome P-450 (CYPIA1) gene. Applications: Suitable for use in ELISA, Western Blot and Gel Super Shift Assays. Other applications not tested. Recommended Dilutions: Gel Super Shift Assays: 4ul to a 15ul final volume of EMSA sample., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.