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Produkte von MONOSAN
MONOSAN® bietet Antikörper und Reagenzien für die Life-Science-Forschung an. Als Markenname der Sanbio B.V. in den Niederlanden begann MONOSAN® 1979 mit der Vermarktung des ersten monoklonalen Anti-Ratte T-Zell-Antikörpers. In den letzten 40 Jahren hat sich das Angebot an Antikörpern enorm erweitert.
Mehr Informationen unter: www.monosan.com
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NEU
Artikelnummer: MON-MON10212
Originally, the 2G9 monoclonal antibody (mAb) was described as identifying a 15 kDa protein found in the cytoplasmic granules of cytotoxic T cells that might be part of a larger 40 kDa molecule, ubiquitously expressed, named p40-TIA-1 and often referred to as TIA-1 in the literature (1, 2). Now, however, there is...
Anwendung: | IHC (paraffin) |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
1.481,00 €
NEU
Artikelnummer: MON-MON10214
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However,...
Anwendung: | IHC (paraffin) |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
258,00 €
NEU
Artikelnummer: MON-MON10215
Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of proteins that have been designated Stats (signal transducers and activators of transcription). The first members of this family to...
Anwendung: | IHC (paraffin) |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
866,00 €
NEU
Artikelnummer: MON-MON10216
Mutations within the BRCA1 gene, localized to chromosome 17q, are believed to account for approximately 45% of families with increased incidence of both early-onset breast cancer and ovarian cancer. The BRCA1 gene is expressed in numerous tissues, including breast and ovary, and encodes a predicted protein of 1,863...
Anwendung: | IHC (paraffin) |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
866,00 €
NEU
Artikelnummer: MON-MON10217
The Yes-associated protein, otherwise known as YAP, is a 14-3-3 binding molecule that was originally recognized by virtue of its ability to bind to the SH3 domain of Yes. The binding of YAP to 14-3-3 requires the phosphorylation of a homologous serine residue (Ser 112) in the YAP 14-3-3 binding motif. The highly...
Anwendung: | IHC (paraffin) |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
998,00 €
NEU
Artikelnummer: MON-MON10218
Recognizes a phosphor-protein of 45kDa, identified as MyoD1. The epitope of this MAb maps between amino acid 180-189 in the C-terminal of mouse MyoD1 protein. It does not cross react with Myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in...
Anwendung: | IHC (paraffin) |
Wirt: | Mouse |
Spezies-Reaktivität: | human, mouse, rat, chicken |
429,00 €
NEU
Artikelnummer: MON-MON10219
Transcription factors containing the POU homeo domain have been shown to be important regulators of tissue-specific gene expression in lymphoid and pituitary differentiation and in early mammalian development. POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them...
Anwendung: | IHC (frozen), IHC (paraffin) |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
813,00 €
NEU
Artikelnummer: MON-MON1022
RIV12 reacts with CD1b, a 44KDa type 1 glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes and T acute lymphoblastic leukemia cells. CD1, type 1 membrane protein, has structural similarity to the MHC class 1 molecule and has been shown to present lipid...
Anwendung: | FC, IHC (frozen), IP, IF, ELISA |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
268,00 €
NEU
Artikelnummer: MON-MON10220
The expression of MDM2 is itself, induced by p53 and may be a way for p53 to self-regulate its activity during the normal cell cycle. However, overexpression of MDM2 results in the loss of p53-regulated growth control and consequently, deregulated cell proliferation. MDM2 also binds to the Retinoblastoma tumor...
Anwendung: | IHC (frozen), IHC (paraffin), WB |
Wirt: | Mouse |
Spezies-Reaktivität: | human, mouse, rat |
558,00 €
NEU
Artikelnummer: MON-MON10221
Recognizes a protein of -55kDa, identified as SOX I 0. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box...
Anwendung: | IHC (frozen), IHC (paraffin) |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
601,00 €
NEU
Artikelnummer: MON-MON10222
The anti-CD43 antibody recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So, a B-lineage population that...
Anwendung: | IHC (paraffin), WB |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
429,00 €
NEU
Artikelnummer: MON-MON10223
ECAD (syn, CD325), 120 kDA, chromosome 16q22.1 (CDH1 gene), is a critical regulator of epithelial junction formation. It interacts with the cytoskeleton through several associated proteins. The ECAD internal domain binds with alpha, beta, gamma and p120 catenin's to anchor the ECAD complex to the actin cytoskeleton...
Anwendung: | IHC (paraffin) |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
1.121,00 €