Produkte von Bethyl Laboratories
Auf der texanischen Ranch von Bethyl Laboratories Inc. in Montgomery, Texas, werden beste polyklonale Antikörper für die klinische und diagnostische Forschung hergestellt. In Zusammenarbeit mit namhaften Wissenschaftlerinnen und Wissenschaftlern identifiziert Bethyl kontinuierlich neue Targets, wodurch ein Antikörperprogramm entsteht, das vergleichbaren Anbietern immer einen Schritt voraus ist. Bethyl Laboratories sind einzigartig in ihrer vollständigen Kontrolle aller Schritte der Antikörperproduktion. Von den veterinären Einrichtungen, über die Entwicklung, Produktion und Validierung in den Laboren konzentriert sich das Team von Bethyl darauf, qualitativ hochwertige Produkte zu liefern. Diese Fokussierung auf Qualität bei jedem einzelnen Schritt und die Integration aller Prozessstufen bedeutet, dass Wissenschaftler*innen sich auf Bethyl-Antikörper verlassen können. Seit 2021 ist Bethyl Laboratories Teil von FORTIS Life Sciences.
Mehr Informationen unter: www.fortislife.com/bethyl-laboratories
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Anti-ZFP106
Artikelnummer: A301-527A
Zinc finger protein homolog 106 (ZFP106) is a C2H2-type zinc finger protein that also contains 2 WD repeats. ZFP106 is highly expressed in striated muscle, brown fat, and developing brain and is regulated by myogenin and nuclear respiratory factor-1 (NRF-1). ZFP106 localizes to the nucleus in association with...
| Schlagworte: | Anti-SH3BP3, Anti-ZNF106, Anti-Zfp-106, Anti-Zinc finger protein 106, Anti-Zinc finger protein 474 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-USP5/IsoT
Artikelnummer: A301-542A
Protein function: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys- 63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an...
| Schlagworte: | Anti-ISOT, Anti-USP5, EC=3.4.19.12, Anti-Isopeptidase T, Anti-Ubiquitin thioesterase 5, Anti-Deubiquitinating enzyme 5,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-ZNF638/NP220
Artikelnummer: A301-548A
Protein function: Early regulator of adipogenesis that works as a transcription cofactor of CEBPs, controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1. Binds to cytidine clusters in double-stranded DNA (PubMed:8647861). May also regulate alternative splicing of target genes...
| Schlagworte: | Anti-NP220, Anti-ZNF638, Anti-Nuclear protein 220, Anti-Zinc finger protein 638, Anti-CTCL-associated antigen se33-1,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-CPSF160
Artikelnummer: A301-580A
Protein function: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is...
| Schlagworte: | Anti-CPSF1, Anti-CPSF160, Anti-CPSF 160 kDa subunit, Anti-Cleavage and polyadenylation specificity factor subunit 1,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-SF3a120/SAP114
Artikelnummer: A301-601A
Protein function: Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also...
| Schlagworte: | Anti-SF3A1, Anti-SAP114, Anti-SF3a120, Anti-SAP 114, Anti-Splicing factor 3A subunit 1, Anti-Spliceosome-associated... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-EHMT1
Artikelnummer: A301-642A
Protein function: Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also weakly methylates 'Lys-27'...
| Schlagworte: | Anti-GLP, Anti-GLP1, Anti-EHMT1, Anti-EUHMTASE1, EC=2.1.1.-, Anti-Eu-HMTase1, EC=2.1.1.43, Anti-H3-K9-HMTase 5,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-14-3-3 Sigma
Artikelnummer: A301-648A-T
Protein function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding...
| Schlagworte: | Anti-SFN, Anti-HME1, Anti-Stratifin, Anti-14-3-3 protein sigma, Anti-Epithelial cell marker protein 1 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-CEP290
Artikelnummer: A301-659A
Protein function: Involved in early and late steps in cilia formation. Its association with CCP110 is required for inhibition of primary cilia formation by CCP110 (PubMed:18694559). May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles...
| Schlagworte: | Anti-CT87, Anti-BBS14, Anti-CEP290, Anti-Cep290, Anti-Nephrocystin-6, Anti-Tumor antigen se2-2, Anti-Cancer/testis antigen... |
| Anwendung: | WB, IP, ICC-IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-eIF5B/IF2
Artikelnummer: A301-744A
Protein function: Plays a role in translation initiation. Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon. GTP binding and hydrolysis induces conformational changes in the...
| Schlagworte: | Anti-IF2, Anti-EIF5B, Anti-eIF-5B, EC=3.6.5.3, Anti-Translation initiation factor IF-2, Anti-Eukaryotic translation... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-ASH1
Artikelnummer: A301-749A
Protein function: Histone methyltransferase specifically methylating 'Lys- 36' of histone H3 (H3K36me). [The UniProt Consortium]
| Schlagworte: | Anti-ASH1L, Anti-huASH1, Anti-KIAA1420, EC=2.1.1.43, Anti-ASH1-like protein, Anti-Lysine N-methyltransferase 2H,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-NIPBL
Artikelnummer: A301-778A
Protein function: Probably plays a structural role in chromatin. Involved in sister chromatid cohesion, possibly by interacting with the cohesin complex. [The UniProt Consortium]
| Schlagworte: | Anti-IDN3, Anti-NIPBL, Anti-Delangin, Anti-SCC2 homolog, Anti-Nipped-B-like protein |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-NUP210
Artikelnummer: A301-795A
Protein function: Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. [The UniProt Consortium]
| Schlagworte: | Anti-POM210, Anti-NUP210, Anti-PSEC0245, Anti-KIAA0906, Anti-Nucleoporin Nup210, Anti-Nuclear pore protein gp210,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €