Produkte von Bethyl Laboratories
Auf der texanischen Ranch von Bethyl Laboratories Inc. in Montgomery, Texas, werden beste polyklonale Antikörper für die klinische und diagnostische Forschung hergestellt. In Zusammenarbeit mit namhaften Wissenschaftlerinnen und Wissenschaftlern identifiziert Bethyl kontinuierlich neue Targets, wodurch ein Antikörperprogramm entsteht, das vergleichbaren Anbietern immer einen Schritt voraus ist. Bethyl Laboratories sind einzigartig in ihrer vollständigen Kontrolle aller Schritte der Antikörperproduktion. Von den veterinären Einrichtungen, über die Entwicklung, Produktion und Validierung in den Laboren konzentriert sich das Team von Bethyl darauf, qualitativ hochwertige Produkte zu liefern. Diese Fokussierung auf Qualität bei jedem einzelnen Schritt und die Integration aller Prozessstufen bedeutet, dass Wissenschaftler*innen sich auf Bethyl-Antikörper verlassen können. Seit 2021 ist Bethyl Laboratories Teil von FORTIS Life Sciences.
Mehr Informationen unter: www.fortislife.com/bethyl-laboratories
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Anti-CHD8
Artikelnummer: A301-224A
Protein function: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation...
| Schlagworte: | Anti-CHD-8, Anti-HELSNF1, Anti-ATP-dependent helicase CHD8, Anti-Helicase with SNF2 domain 1,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-BRF1
Artikelnummer: A301-228A
Protein function: General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter. [The UniProt Consortium]
| Schlagworte: | Anti-BRF, Anti-hBRF, Anti-BRF1, Anti-BRF-1, Anti-TAF3B2, Anti-TFIIIB90, Anti-hTFIIIB90, Anti-B-related factor 1,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-PTRF
Artikelnummer: A301-269A
Protein function: Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues (PubMed:18056712, PubMed:18191225, PubMed:19726876). Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of...
| Schlagworte: | Anti-PTRF, Anti-FKSG13, Anti-Cavin-1, Anti-Caveolae-associated protein 1, Anti-Polymerase I and transcript release factor |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-XPF/ERCC4
Artikelnummer: A301-315A
Protein function: Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link. [The UniProt Consortium]
| Schlagworte: | Anti-ERCC4, Anti-ERCC11, EC=3.1.-.-, Anti-DNA repair endonuclease XPF, Anti-DNA excision repair protein ERCC-4, Anti-DNA... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-PSF/SFPQ
Artikelnummer: A301-320A
Protein function: DNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as a heteromer with NONO. Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic...
| Schlagworte: | Anti-PSF, Anti-SFPQ, Anti-hPOMp100, Anti-100 kDa DNA-pairing protein, Anti-PTB-associated-splicing factor, Anti-Splicing... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-CSB/ERCC6
Artikelnummer: A301-345A
ERCC6, also known as Cockayne syndrome B protein, is involved in DNA repair in response to UV exposure. ERCC6 has been reported to display ATPase and helicase activity and functions as a transcriptional regulator. Mutations in ERCC6 are the cause of Cockayne syndrome type B (CSB), cerebro-oculo-facio-skeletal...
| Schlagworte: | Anti-PGBD3, Anti-PiggyBac transposable element-derived protein 3 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-CPSF68
Artikelnummer: A301-356A
Protein function: Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping. [The...
| Schlagworte: | Anti-CPSF6, Anti-CFIM68, Anti-CFIm68, Anti-Protein HPBRII-4/7, Anti-CPSF 68 kDa subunit, Anti-Pre-mRNA cleavage factor Im... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-CPSF68
Artikelnummer: A301-358A
Protein function: Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping. [The...
| Schlagworte: | Anti-CPSF6, Anti-CFIM68, Anti-CFIm68, Anti-Protein HPBRII-4/7, Anti-CPSF 68 kDa subunit, Anti-Pre-mRNA cleavage factor Im... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-ATXN2L
Artikelnummer: A301-369A
Protein function: Involved in the regulation of stress granule and P-body formation. [The UniProt Consortium]
| Schlagworte: | Anti-A2D, Anti-ATXN2L, Anti-Ataxin-2-like protein, Anti-Ataxin-2 domain protein, Anti-Ataxin-2-related protein |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-SART1
Artikelnummer: A301-422A
Protein function: Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA. [The UniProt Consortium]
| Schlagworte: | Anti-SART1, Anti-SART-1, Anti-hSnu66, Anti-Hom s 1, Anti-hSART-1, Anti-SNU66 homolog, Anti-U4/U6.U5 tri-snRNP-associated... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-NP95/UHRF1
Artikelnummer: A301-470A
Protein function: Multidomain protein that acts as a key epigenetic regulator by bridging DNA methylation and chromatin modification. Specifically recognizes and binds hemimethylated DNA at replication forks via its YDG domain and recruits DNMT1 methyltransferase to ensure faithful propagation of the DNA methylation...
| Schlagworte: | Anti-hNp95, Anti-UHRF1, Anti-hUHRF1, Anti-HuNp95, Anti-ICBP90, EC=2.3.2.27, Anti-Nuclear protein 95, Anti-RING finger... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-ZFP106
Artikelnummer: A301-527A
Zinc finger protein homolog 106 (ZFP106) is a C2H2-type zinc finger protein that also contains 2 WD repeats. ZFP106 is highly expressed in striated muscle, brown fat, and developing brain and is regulated by myogenin and nuclear respiratory factor-1 (NRF-1). ZFP106 localizes to the nucleus in association with...
| Schlagworte: | Anti-SH3BP3, Anti-ZNF106, Anti-Zfp-106, Anti-Zinc finger protein 106, Anti-Zinc finger protein 474 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €