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Kanamycin A (sulfate)
Artikelnummer: Cay15321-5
Kanamycin A is a broad spectrum antibiotic isolated from a soil streptomyces (S. kanamyceticus). This aminoglycoside alters translation by prokaryotic ribosomes, resulting in bacterial cell death. In molecular biology, kanamycin A is used as a selective agent to isolate transformants that are expressing a kanamycin...
| Schlagworte: | Ophtalmokalixan,... |
| Anwendung: | Antibiotic |
| CAS | 25389-94-0 |
| MW: | 582.6 D |
ab 78,00 €
Tobramycin
Artikelnummer: Cay14596-50
Tobramycin is an aminoglycoside antibiotic. It binds to the 30S ribosomal subunit, inhibiting protein synthesis. Tobramycin is active against a variety of Gram-positive and Gram-negative bacteria, including several strains of S. aureus, P. aeruginosa, E. coli, K. pneumoniae, and Enterobacter (mean MICs = 0.2, 0.6,...
| Schlagworte: | Deoxykanamycin B, Distobram, Gernebcin, NSC 180514,... |
| Anwendung: | Aminoglycoside antibiotic |
| CAS | 32986-56-4 |
| MW: | 467.5 D |
ab 44,00 €
Amikacin
Artikelnummer: Cay15405-1
Amikacin is an aminoglycoside antibiotic derived from kanamycin A. Like other aminoglycosides, amikacin binds to bacterial ribosomes and disrupts translation. However, the specific binding sites differ between different aminoglycoside antibiotics, as do the mechanisms of resistance. Amikacin is effective against...
| Schlagworte: | Antibiotic BB-K 8, BAY 41-6551, BB-K 8, Lukadin, Potentox,... |
| Anwendung: | Aminoglycoside antibiotic |
| CAS | 37517-28-5 |
| MW: | 585.6 D |
ab 67,00 €
Nourseothricin (sulfate)
Artikelnummer: Cay16227-1
Nourseothricin is a broad-spectrum antibiotic produced by Streptomyces variants that inhibits protein synthesis by inducing miscoding. It is commonly used as a dominant selection antibiotic for genetically modified bacteria, yeasts, fungi, protozoa, plants, and mammalian cells. Selection of recombinant strains is...
| Schlagworte: | clonNAT, Streptothricin, nourseothricin, monosulfate |
| Anwendung: | Broad-spectrum antibiotic |
| CAS | 96736-11-7 |
| MW: | 1359.5 D |
ab 44,00 €
Gatifloxacin
Artikelnummer: Cay14290-1
Gatifloxacin is a fluoroquinolone antibiotic which inhibits bacterial DNA gyrase (IC50 = 0.109 µg/ml) and topoisomerase IV (IC50 = 13.8 µg/ml). It is much less effective against HeLa cell topoisomerase II (IC50 = 265 µg/ml). Gatifloxin has been used as a broad-spectrum oral antibiotic, but it can produce dysglycemia...
| Schlagworte: | AM1155, BMS 206584-01, PD 135432,... |
| Anwendung: | Antibiotic, Metabolic studies |
| CAS | 112811-59-3 |
| MW: | 375.4 D |
ab 61,00 €
Spectinomycin (hydrochloride hydrate)
Artikelnummer: Cay14324-1
Spectinomycin is an aminocyclitol antibiotic produced by S. spectabilis that is active against Gram-negative and Gram-positive bacteria. Spectinomycin inhibits protein synthesis by binding to the 30S ribosomal subunit and interfering with peptidyl tRNA translocation. Mutations in the gene for ribosomal protein S5...
| Schlagworte: | (5aR,9aR,10aS)-decahydro-4aR,7S,9S-trihydroxy-2R-methyl-6S,8R-bis(methylamino)-4H-pyrano[3-b][1,4]benzodioxin-4-one,... |
| Anwendung: | Antibiotic |
| CAS | 22189-32-8 |
| MW: | 495.4 D |
55,00 €
Neamine (hydrochloride)
Artikelnummer: Cay21752-25
Neamine is a natural degradation product of neomycin (Cay-14287) and is a common core molecule used in the synthesis of aminoglycoside antibiotics. Formulations containing neamine are used as antibiotic agents.Formal Name: 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl)-D-streptamine,...
| Schlagworte: | Neomycin A, 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl)-D-streptamine, tetrahydrochloride |
| Anwendung: | Neomycin degradation product |
| CAS | 15446-43-2 |
| MW: | 468.2 D |
ab 66,00 €
Streptomycin (sulfate)
Artikelnummer: Cay21211-25
Streptomycin is an aminoglycoside antibiotic that inhibits growth of both Gram-negative (MICs = 1 and 16 µg/mL for K. pneumoniae and S. marcescens, respectively) and Gram-positive bacteria (MIC = 0.25 µg/mL for S. pneumoniae). It inhibits growth of M. tuberculosis H37Rv (MIC = 5 µg/mL) and of susceptible strains...
| Schlagworte: | O-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1->4)-N1,N3-bis(aminoi... |
| Anwendung: | Antibacterial antibiotic, protein biosynthesis inhibitor |
| CAS | 3810-74-0 |
| MW: | 728.7 D |
ab 36,00 €
Sisomicin
Artikelnummer: Cay21046-50
Sisomicin is a broad-spectrum aminoglycoside antibiotic originally isolated from M. inyoensis. It is active against Gram-positive and Gram-negative bacteria including B. subtilis, S. aureus, E. coli, and P. aeruginosa among others (MICs = 0.01-0.75 µg/ml) but is less active against P. multocida and V. coli (MICs =...
| Schlagworte: | Antibiotic 6640, SCH 13475,... |
| Anwendung: | Antibacterial, Protein biosynthesis inhibitor |
| CAS | 32385-11-8 |
| MW: | 447.5 D |
ab 44,00 €
Apramycin (sulfate hydrate)
Artikelnummer: Cay19688-500
Apramycin is an aminoglycoside antibiotic first isolated from S. tenebrarius. It is active against a variety of Gram-positive and Gram-negative bacteria, including strains which produce aminoglycoside-modifying enzymes. Apramycin inhibits protein synthesis in bacteria both in vivo and in vitro.Formal Name:...
| Schlagworte: | Nebramycin II,... |
| Anwendung: | Antibiotic |
| MW: | 539.6 D |
ab 40,00 €
Netilimicin (sulfate)
Artikelnummer: Cay26666-10
Netilimicin is an aminoglycoside antibiotic. It is active against S. aureus, N. gonorrhoeae, E. coli, P. mirabilis, and P. aeruginosa (MICs = 0.4, 3.1, 0.8, 1.6, and 0.4 µg/ml, respectively) as well as Enterococci, Enterobacter, Citrobacter, and Klebsiella species (MICs = 3.1, 0.4, 0.8, and =0.2 µg/ml,...
| Schlagworte: | Netillin, Netilyn,... |
| Anwendung: | Aminoglycoside antibiotic |
| CAS | 56391-57-2 |
| MW: | 720.8 D |
ab 133,00 €
Micronomicin (sulfate)
Artikelnummer: Cay27951-250
Micronomicin is an aminoglycoside antibiotic originally isolated from Micromonospora. It is active against S. aureus, B. subtilis, B. cereus, E. coli, and K. pneumoniae (MICs = 0.001-8.3 µg/ml) and inactive against C. albicans and A. niger (MICs = >10 µg/ml).Formal Name:...
| Schlagworte: | Antibiotic XK-62-2, Gentamicin C2b, Sagamicin,... |
| Anwendung: | Antibacterial aminoglycoside antibiotic, protein biosynthesis inhibitor |
| CAS | 66803-19-8 |
| MW: | 463.6 D |
ab 49,00 €
Dihydrostreptomycin (sulfate)
Artikelnummer: Cay27879-50
Dihydrostreptomycin is an aminoglycoside antibiotic and a derivative of streptomycin (Cay-21211). It is active against B. subtilis, K. pneumoniae, S. marcescens, S. aureus, P. aeruginosa, and M. tuberculosis (MICs = 0.07, 0.08, 0.09, 0.06, 0.8, and 5.7 µg/ml, respectively). It interferes with bacterial protein...
| Schlagworte: | O-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1->2)-O-5-deoxy-3-C-(hydroxymethyl)-alpha-L-lyxofuranosyl-(1->4)-N1,N3-b... |
| Anwendung: | Aminoglycoside antibiotic, Antibacterial, Protein biosynthesis inhibitor |
| CAS | 5490-27-7 |
| MW: | 730.7 D |
ab 111,00 €
Paromomycin (sulfate)
Artikelnummer: Cay23634-5
Paromomycin is an aminoglycoside antibiotic that is effective against Gram-negative and Gram-positive bacteria (MICs = 0.08-3.9 µg/ml). It also has antiprotozoal properties and decreases the parasite burden of mice infected with the leishmanial strain L. tropica when administered at doses of 50 mg/kg and 15 mg/kg,...
| Schlagworte: | O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1->3)-O-beta-D-ribofuranosyl-(1->5)-O-[2-amino-2-deoxy-alpha-D-glucopyranos... |
| Anwendung: | Antibiotic, protein biosynthesis inhibitor |
| CAS | 1263-89-4 |
| MW: | 615.6 D |
ab 86,00 €